Abi

Scialog

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Advancing BioImaging

2021-2023

Four landmark innovations in imaging have been recognized with recent Nobel Prizes — 3-D tomography/MRI, genetically encoded fluorescent proteins, super-resolution fluorescence microscopy, and atomic resolution electron microscopy. While none of these advances delivers cellular resolution deep in tissue, they do provide models for how such technical advances occur. Those new technologies were each developed collaboratively through interactions among physicists, chemists, engineers, software developers, biologists and clinicians. In the same manner, the goal of this Scialog will be to assemble approximately 50 early-career scientists with wide-ranging expertise who wish to apply their skills toward developing the next generation of imaging technologies that will enhance the ability to study tissues at cellular or sub-cellular resolution and to map biological processes within and throughout organisms.

Fellows & Facilitators

Fellows
  • Shiva Abbaszadeh
    Electrical and Computer Engineering
    University of California, Santa Cruz

    Benjamin Bartelle,
    Biological and Health Systems Engineering
    Arizona State University

    Carolyn Bayer
    Biomedical Engineering
    Tulane University

    Eszter Boros
    Chemistry
    Stony Brook University SUNY

    Joshua Brake
    Engineering
    Harvey Mudd College

    Molly Bright
    Biomedical Engineering, Physical Therapy and Human Movement Sciences,
    Northwestern University

    Dylan Burnette
    Cell and Developmental Biology
    Vanderbilt University Medical Center

    Kevin Cash
    Chemical and Biological Engineering
    Colorado School of Mines

    Fanny Chapelin
    Bioengineering
    University of California, San Diego

    Huanyu Cheng
    Engineering Science and Mechanics
    Pennsylvania State University

    Shwetadwip Chowdhury
    Electrical and Computer Engineering
    University of Texas at Austin

    Scott Cushing
    Chemistry and Chemical Engineering
    California Institute of Technology

    Mini Das
    Physics
    University of Houston

    Shawn Davidson
    Lewis-Sigler Institute
    Princeton University    

    Allison Dennis
    Chemical Engineering and Bioengineering
    Northeastern University

    Joyoni Dey
    Physics and Astronomy
    Louisiana State University

    Alexandra Dickinson
    Biology
    University of California, San Diego

    Bin Dong
    Chemistry and Biochemistry
    University of Arkansas

    Meghan Driscoll
    Pharmacology
    University of Minnesota Twin Cities  

    Uzay Emir
    School of Health Science
    Purdue University

    Candace Fleischer
    Radiology & Imaging Sciences
    Emory University

    Ashwanth Francis
    Institute of Molecular Biophysics | Biological Sciences
    Florida State University

    Nick Galati
    Biology
    Western Washington University

    Ruixuan Gao
    Chemistry and Biological Sciences
    University of Illinois at Chicago

    Anna-Karin Gustavsson
    Chemistry
    Rice University

    Arnold Hayer
    Biology
    McGill University

    Ying S. Hu
    Chemistry
    University of Illinois at Chicago

    Ulugbek Kamilov
    Computer Science and Engineering
    Washington University in St. Louis

    Kathryn Keenan
    Applied Physics Division
    National Institute of Standards and Technology

    Yevgenia Kozorovitskiy
    Neurobiology
    Northwestern University

    Melike Lakadamyali
    Physiology
    University of Pennsylvania

    Fan Lam
    Bioengineering
    University of Illinois at Urbana-Champaign

    Matthew Lew
    Electrical and Systems Engineering
    Washington University in St. Louis

    Jing Liu
    Physics
    Indiana University-Purdue University Indianapolis

    Yi-Chih Lin
    Chemistry
    University of Texas at Austin

    Qian Liu
    Institute of Parasitology
    McGill University

    Matthew Lovett-Barron
    Division of Biological Sciences, Neurobiology Section
    University of California, San Diego

    Xiaocun Lu
    Chemistry and Biomolecular Science
    Clarkson University     

    Morteza Mahmoudi
    Radiology and Precision Heath
    Michigan State University

    Divita Mathur
    Chemistry
    Case Western Reserve University

    Dylan McCreedy
    Biology
    Texas A&M University, College Station

    Ryan J. McGorty
    Physics and Biophysics
    University of San Diego

    Aseema Mohanty
    Electrical and Computer Engineering
    Tufts University

    Luke Mortensen
    Regenerative Bioscience Center / Chemical, Materials and Biomedical Engineering
    University of Georgia

    Arnab Mukherjee
    Chemical Engineering, Biological Engineering
    University of California, Santa Barbara

    Abdoulaye Ndao
    Electrical and Computer Engineering
    Boston University

    Girgis Obaid
    Bioengineering
    University of Texas at Dallas

    Sapun Parekh
    Biomedical Engineering
    University of Texas at Austin

    Paris Perdikaris
    Mechanical Engineering and Applied Mechanics
    University of Pennsylvania

    Rosario Porras-Aguilar
    Physics & Optical Sciences
    University of North Carolina at Charlotte

    Lisa Poulikakos
    Mechanical and Aerospace Engineering
    University of California, San Diego

    Colin Rathbun
    Chemistry
    Dickinson College

    Aniruddha Ray
    Physics & Astronomy
    University of Toledo

    Crystal Rogers
    Anatomy, Physiology, and Cell Biology
    University of California, Davis

    Devleena Samanta
    Chemistry
    University of Texas at Austin

    Mimi Sammarco
    Surgery
    Tulane School of Medicine

    Danielle Schmitt
    Chemistry and Biochemistry
    University of California, Los Angeles

    Johannes Schöneberg
    Pharmacology and Chemistry & Biochemistry
    University of California, San Diego

    Ferdinand Schweser
    Neurology
    SUNY – University at Buffalo

    Mark Sellmyer
    Radiology
    University of Pennsylvania

    Douglas Shepherd
    Physics
    Arizona State University – Tempe Campus

    Lingyan Shi
    Bioengineering
    University of California, San Diego

    Seunghyun (Seu) Sim
    Chemistry
    University of California, Irvine

    Ellen Sletten
    Chemistry and Biochemistry
    UCLA

    Barbara Smith
    Biological and Health Systems Engineering
    Arizona State University

    Bryan Spring
    Physics
    Northeastern University

    Lei Tian
    Electrical and Computer Engineering
    Boston University              

    Srigokul Upadhyayula
    Molecular and Cell Biology
    University of California, Berkeley

    David Van Valen
    Biology and Bioengineering
    California Institute of Technology

    Alexandra Walsh
    Biomedical Engineering
    Texas A&M University, College Station

    Ping Wang
    Radiology
    Michigan State University

    Rongsheng (Ross) Wang
    Chemistry
    Temple University

    Lu Wei
    Chemistry and Chemical Engineering
    Caltech

    Katharine White
    Chemistry and Biochemistry
    University of Notre Dame

    Heather M. Whitney
    Radiology
    University of Chicago

    Stefan Wilhelm
    Stephenson School of Biomedical Engineering
    University of Oklahoma

    Sheng Xu
    Nanoengineering, Bioengineering, and Electrical and Computer Engineering
    University of California, San Diego               

    Stephen Yi
    Biomedical Engineering & Oncology
    University of Texas at Austin 

    Sixian You
    Electrical Engineering and Computer Science
    Massachusetts Institute of Technology

    Ruobo Zhou
    Chemistry
    Pennsylvania State University
Facilitators
  • Samuel Achilefu
    University of Texas Southwestern Medical Center
  • Matthew Bogyo
    Stanford University Medical Center
  • Agata Exner
    Case Western Reserve University
  • Maryellen Giger
    University of Chicago

    Matthew Kupinski
    University of Arizona
  • George Langford
    Syracuse University
  • Kristen Maitland
    Texas A&M University
  • Anna Moore
    Michigan State University

    Kyle Myers
    Puente Solutions LLC

    Brian Pogue
    University of Wisconsin-Madison
  • Jennifer Prescher
    University of California, Irvine

    Brad Smith
    Notre Dame
  • Min Wei
    Columbia University
  • Jin Zhang
    University of California, San Diego

Team Awards

Goal: to advance fundamental imaging science and improve its ability to impact human health and our understanding of biological structures and their function.

2023 Team Awards

PETinIVIS: A Modular PET Insert to Enable Simultaneous Acquisition of Optical and PET Imaging Data in Small Animals 

  • Eszter Boros
    Chemistry
    University of Wisconsin – Madison 1
  • Shiva Abbaszadeh
    Electrical and Computer Engineering
    University of California, Santa Cruz 1

Developing Multi-Angle Synthesized Ultrasound Tomography

  • Shwetadwip Chowdhury
    Electrical and Computer Engineering
    University of Texas at Austin 2
  • Heather M. Whitney
    Radiology, University of Chicago 3

Specific and Quantitative MRI Imaging for Longitudinal Cell Fate Tracking

  • Dylan McCreedy
    Biology
    Texas A&M University, College Station 1
  • Fanny Chapelin
    Bioengineering
    University of California, San Diego 1

Quantitative, Spatially Resolved Analysis of Single-Cell and Single-Organelle Metabolism

  • Seunghyun (Seu) Sim
    Chemistry
    University of California, Irvine 1
  • Ruixuan Gao
    Chemistry and Biological Sciences
    University of Illinois Chicago 3
  • Shawn Davidson
    Medicine, Northwestern University 1

Exploring the Mechano-Metabolic Landscape of a Beating Ciliary Array 

  • Yi-Chih Lin
    Chemistry
    University of Texas at Austin 2
  • Nick Galati
    Biology, Western Washington University 2
  • Lingyan Shi
    Bioengineering
    University of California, San Diego 2

Sketch-Based Retrieval and Clustering of Neurons in Large Microscopy Data

  • Dylan McCreedy
    Biology
    Texas A&M University, College Station 2
  • Meghan Driscoll
    Pharmacology
    University of Minnesota Twin Cities 2

Quantum-Enhanced Fluorescent Imaging with Entangled Photons 

  • Scott Cushing
    Chemistry and Chemical Engineering
    California Institute of Technology 2
  • Jing Liu
    Physics
    Purdue University 2

3D Dynamics Quantification with Differential Dynamic Light-Field Microscopy 

  • Lei Tian
    Electrical and Computer Engineering
    Boston University 2
  • Ryan J. McGorty
    Physics and Biophysics
    University of San Diego 2

Beam Shaping Metasurfaces Using DNA Alignment and Liquid Crystals

  • Rosario Porras-Aguilar
    Physics & Optical Sciences
    University of North Carolina at Charlotte 1
  • Divita Mathur
    Chemistry
    Case Western Reserve University 1

1 Funded by RCSA & Frederick Gardner Cottrell Foundation
2 Funded by CZI
3 Funded by Walder Foundation

2022 Team Awards

Real-time AI for Programmable Training Arrays

  • Shiva Abbaszadeh
    Electrical and Computer Engineering
    University of California, Santa Cruz *

    Heather Whitney
    Radiology
    University of Chicago *

Making Lenses Smart for Optical Imaging and Beyond

  • Yevgenia Kozorovitskiy
    Neurobiology
    Northwestern University †

    Abdoulaye Ndao
    Electrical and Computer Engineering
    Boston University ^

Democratizing Access to Macroscopic Bioimaging

  • Joshua Brake
    Engineering
    Harvey Mudd College *

    Kevin Cash
    Chemical and Biological Engineering
    Colorado School of Mines *

Improving MRI Detection Limits

  • Mark Sellmyer
    Radiology
    University of Pennsylvania *        

    Arnab Mukherjee
    Chemical Engineering and Biological Engineering
    University of California, Santa Barbara *

MRI with Molecular Specificity for a New Realm of Neurodevelopmental Research

  • Kathryn Keenan
    Applied Physics Division
    National Institute of Standards and Technology ^

    Crystal Rogers
    Anatomy, Physiology, and Cell Biology
    University of California, Davis ^

    Ulugbek Kamilov
    Computer Science and Engineering
    Washington University in St. Louis ^

4D Imaging and Tracking to Resolve Organelle Form vs. Function

  • Alexandra Walsh
    Biomedical Engineering
    Texas A&M University, College Station *

    Johannes Schöneberg
    Pharmacology and Chemistry & Biochemistry
    University of California, San Diego *

Live tissue Clearing of Lymph Nodes Through Programmed Dendritic Cells

  • Ying Hu
    Chemistry
    University of Illinois at Chicago ^

    Seunghyun (Seu) Sim
    Chemistry
    University of California, Irvine ^

High-speed 4D Morphodynamic Analysis of Migrating Cells

  • Arnold Hayer
    Biology
    McGill University ^

    Rosario Porras-Aguilar
    Physics & Optical Sciences
    University of North Carolina at Charlotte ^

Transforming Imaging Collection in the Brain

  • Luke Mortensen
    Regenerative Bioscience Center / Chemical, Materials and Biomedical Engineering
    University of Georgia *  
                                          
    Huanyu Cheng
    Engineering Science and Mechanics
    Pennsylvania State University *        

In Situ Protein Sequencing by Multiplexed Real-Time Single Molecule Imaging

  • Stephen Yi
    Biomedical Engineering & Oncology
    University of Texas at Austin ^

    Ruixuan Gao
    Chemistry and Biological Sciences
    University of Illinois Chicago †

* Funded by CZI
^ Funded by RCSA/FGCF
† Funded by Walder Foundation

2021 Team Awards

NeedleScope: Developing the Smallest Microscope for Bioimaging

  • Aseema Mohanty
    Electrical and Computer Engineering
    Tufts University
  • Sixian You
    Electrical Engineering and Computer Science
    Massachusetts Institute of Technology

Funded by RCSA

4-D Molecular Tracking Using Kilohertz Framerate Multi-Modal Microscopy

  • Nick Galati
    Biology
    Western Washington University
  • Shannon Quinn
    Computer Science
    University of Georgia
  • Doug Shepherd
    Physics
    Arizona State University

Funded by RCSA

Nanophotonic Probes for Ultra-Deep Functional Multiphoton Imaging

  • Luke Mortensen
    Chemical, Materials and Biomedical Engineering
    University of Georgia
  • Aniruddha Ray
    Physics & Astronomy
    University of Toledo

Funded by RCSA

Light-Sheet Imaging of 3D Bioprinted Islet Organoids Structure and Function

  • Yevgenia Kozorovitskiy
    Neurobiology
    Northwestern University
  • Ping Wang
    Radiology
    Michigan State University

Funded by RCSA

Enabling Noninvasive Lipid Profiling with Intermodal Deep Learning

  • Benjamin Bartelle
    Biological and Health Systems Engineering
    Arizona State University Fulton School of Engineering

    Ulugbek Kamilov
    Computer Science & Engineering / Electrical & Systems Engineering
    Washington University in St. Louis

    Lu Wei
    Chemistry and Chemical Engineering
    California Institute of Technology
  • Funded by CZI

Chip-scale Light Sheet for High Spatiotemporal Resolution Imaging

  • Aseema Mohanty
    Electrical and Computer EngineeringTufts University

    Srigokul Upadhyayula
    Molecular and Cell Biology
    University of California, Berkeley

    Funded by CZI

Deep Tissue Photoacoustic Imaging with Degradable Inorganic Nanoparticles

  • Carolyn Bayer
    Biomedical Engineering
    Tulane University

    Allison Dennis
    Biomedical Engineering
    Boston University
  • Funded by CZI

Machine Learning to Identify Soft Tissue Molecular Signatures 

  • Carolyn Bayer
    Biomedical Engineering
    Tulane University

    Sapun Parekh
    Biomedical Engineering
    University of Texas at Austin

    Paris Perdikaris
    Mechanical Engineering and Applied Mechanics
    University of Pennsylvania

    Funded by CZI

Microendoscopy-Guided Diagnosis and Treatment of Early-Stage Ovarian Cancer

  • Barbara Smith
    Biological and Health Systems Engineering
    Arizona State University

    Bryan Spring
    Physics
    Northeastern University

    Funded by CZI

Wide-Field, Single-Pixel Fluorescence Imaging with On-Chip Nanophotonics

  • Lisa Poulikakos
    Mechanical and Aerospace Engineering
    University of California, San Diego

    Douglas Shepherd
    Physics
    Arizona State University

    Funded by CZI

Conference Booklets

2021 Scialog ABI Conference Booklet
2022 Scialog ABI Conference Booklet
2023 Scialog ABI Conference Booklet

SPONSORS

Additional Support

Walder Foundation